Our aims were to investigate vitamin A and E status during lactation and the determinants of breast milk content for the appropriate nutrition of the infant in a study with nursing Brazilian women. We hypothesized that both inadequate intake and the lipoprotein distribution of vitamin A and E during lactation could have an impact on their breast milk levels from early- to mid-lactation. Nineteen adult lactating women participated in this longitudinal observational study, in which dietary records, blood and mature breast milk samples were collected for the analysis of vitamin A and E, and carotenoids in early- (2nd to 4th week) and mid-lactation (12th to 14th week). Nutrient intake was balanced by the Multiple Source Method (MSM), and the intake of vitamin A and E was inadequate in 74 and 100% of the women, respectively. However, these results were not reflected in low serum concentrations of retinol and only 37% of the volunteers were vitamin E deficient according to the blood biomarker. As lactation progressed, vitamin A and E status worsened, and this was clearly observed by the decrease in their content in breast milk. The reduced content of vitamin A and E in the breast milk was not related to their distribution in lipoproteins. Taken together, the contents of vitamin A and E in breast milk seemed to be more sensitive markers of maternal nutrition status than respective blood concentrations, and dietary assessment by the MSM in early lactation was sensitive to indicate later risks of deficiency and should support maternal dietary guidance to improve the infant's nutrition.
A recent study showed that BRP extract was able to reduce the proportions of red and orange bacterial complexes at the concentration of 1600 μg/mL, while chlorhexidine reduced only those from the red complex . The differences between our findings and those of Miranda et al.  can be explained by the treatment regimen used in our studies. While Miranda et al.  performed two 1 min daily treatments during biofilm formation, we grew biofilm cultures for six days to a mature state and then treated them for 24 h. This protocol was selected to mimic the systemic use of antibiotics, which are normally administered for one/two week(s). Although mature biofilms are more resistant to antimicrobials than immature biofilms, the effective concentration of BRP extract for a 24 h treatment (400 μg/mL) was four-fold lower than that used for daily treatments (1600 μg/mL) . Once the contact period of the BRP extract with biofilm cells was longer in our study, we reasoned that testing a lower effective concentration of the extract would be more appropriate, particularly because our findings showed that increasing BRP extract concentration above 400 μg/mL does not augment the inhibitory effects of the extract against mature biofilms.
In this context, considering the relevance of this world class oil & gas province, this paper intends to describe how the team is facing the challenge of generating extra value through investments in mature fields in the Campos Basin, considering its decision-making process, the increase in the recovery factor, reduction of costs, strategic alliances, and articulation with Regulatory Agencies.
The mitigation of environmental problems requires both national and international agreements, since they have possible global effects. In nationwide conventions (such as Rio, 92; Kyoto Protocol, 1997), a common conclusion has been the need to reduce greenhouse emissions, especially those due to CO2 from burning fossil fuels. For example, Kyoto protocol has established that industrialized nations should reduce their emissions over 2008-2012 by at least 5.2% compared with the 1990 levels. An alternative USA proposal is based on reducing greenhouse emissions by capturing and stockpiling CO2 in natural sites like oceans, caverns, depleted oil reservoir, etc. This paper presents a physical description and an economic analysis of a project to capture and inject CO2 in oil production and its storage in the depleted oil reservoir located in a mature field in Brazil. The Stella Software has been used in order to analyze de dynamics of the whole process of CO2 sequestration in enhanced oil recovery, considering each step of the process with its respective energy requirements. The main findings of this have the following benefits: i) reduction in the emission of CO2; ii) extension of the operational life of the reservoir; and iii) improvement and development of technology to promote EOR in mature fields. Results indicate that project NPV is around US$ 3.2 million, what is significant for a small mature field. Additionally, it contributes by removing greenhouse gases (GHG) from the atmosphere by storing 0.73 million tons of CO2 over a period of 20 years. Project feasibility, as expected, was found to be very sensitive to oil price, oil production, and CAPEX.
Brazilian Blowout Anti-Aging Correct + Prevent Spray is designed to rebuild damaged fibers from within in matured, dull, weak, or thinning hair while correcting and preventing the symptoms of aging. This leave-in is formulated with an advanced micro-reparative system loaded with clinically proven actives and purified plant proteins that instantly correct years of damage which can cause premature aging while restoring the look and feel of younger hair. Brazilian Blowout Anti-Aging Correct + Prevent Spray is infused with a protective polymer that decreases breakage and blow dry time as it combats frizz and calms wiry grays. Strands are thickened, smooth, and appear to be years younger. Signs of aging are immediately drastically decreased, humidity is naturally neutralized, and color retention is improved with prolonged application.
As the mature fields reach mid-life, there are signs of reservoir depletion. Water and gas ratios have increased and decline rates are accelerating. Increased water and gas production already caps oil production rates, limited by FPSO liquids and gas processing capacity.
Since the Brazilian state-owned company Petrobras started the selling process of concessions in mature Fields, several independent companies started to operate these fields, demanding investments in technologies, training, and research to increase the recovery factor and optimize the production.
These are mature onshore basins still prolific after decades of production. They have a myriad of profitable opportunities to medium and small operators. The challenge is determining what can be done to increase their Recovery Factor Some of the actions includes but are not limited to stimulation, re-completion, chemical\\water\\steam injection, modification of tax structures, extensive infill drilling, accurate reservoir monitoring and management, and the optimization and operation of proper production methodologies (aka selection of artificial lift methods).
The strong predominance of magmatic (Th/U >0.2) zircon grains in quartz sandstones from 10 locations in the Brazilian Shield, as measured by sensitive high-resolution ion microprobe (SHRIMP), introduces a strong bias in the tectonic interpretation of source terrains, because the metamorphic sources remain undetected in the detrital population. Zircon grains from many mature, and some immature, sedimentary terrains show Th/U ratios >0.2, ratios commonly considered magmatic, complemented by the near absence of metamorphic Th/U ratios 59ce067264